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Insights Cataract Refract Surg : Insights in Cataract and Refractive Surgery

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Original Article 중등도의 푹스각막이상증 환자에서 백내장 수술 후 임상양상
송명선, 김동현
Clinical manifestations after cataract surgery in patients with moderate Fuchs corneal endothelial dystrophy
Myung-Sun Song, Dong Hyun Kim
Insights in Cataract and Refractive Surgery [Epub ahead of print]
DOI: https://doi.org/10.1234/icrs.25.006
Published online: February 28, 2025

Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea

Received: 15 January 2025   • Revised: 20 February 2025   • Accepted: 26 February 2025
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Purpose
The aim of this study was to analyze the clinical outcomes of cataract surgery in patients with moderate Fuchs endothelial corneal dystrophy (FECD) in whom central endothelial cells could not be observed using specular microscopy.
Methods
This retrospective study included nine eyes in seven patients diagnosed with FECD who underwent phacoemulsification at a single institution between January 2023 and November 2024. A single experienced corneal specialist performed slit-lamp examination and phacoemulsification. Best-corrected visual acuity (BCVA), specular microscopy, and central corneal thickness (CCT) measurements were performed preoperatively and postoperatively, and the outcomes were compared.
Results
The mean age of the patients was 69.8±6.5 years. Two were male patients and five were female patients. The mean preoperative CCT was 559.5±51.8 μm and the mean peripheral endothelial cell density was 599.3±129.4 cells/mm². BCVA significantly improved in all patients postoperatively, with a mean logMAR BCVA improving from 0.65±0.52 preoperatively to 0.19±0.14 postoperatively (P=0.002). The mean CCT showed no significant change (preoperative, 559.6±51.8 μm; postoperative, 566.8±45.1 μm; P=0.218). In patients with follow-up longer than 6 months, an increase in CCT was observed at 30 days postoperatively, but CCT returned to preoperative levels after 90 days.
Conclusion
In patients with moderate-to-severe FECD in whom central endothelial cells cannot be measured, phacoemulsification may provide favorable visual outcomes if peripheral endothelial cells are observed and corneal edema is absent preoperatively.

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Insights Cataract Refract Surg : Insights in Cataract and Refractive Surgery
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